Download PDF by Prasanthi Karna, Lily Yang (auth.), George G. Chen Dr, Paul: Apoptosis in Carcinogenesis and Chemotherapy: Apoptosis in

By Prasanthi Karna, Lily Yang (auth.), George G. Chen Dr, Paul B.S. Lai Dr (eds.)

ISBN-10: 1402095961

ISBN-13: 9781402095962

ISBN-10: 140209597X

ISBN-13: 9781402095979

The function of this e-book is to supply info on apoptotic procedures fascinated by significant neoplastic illnesses and their translations into rising anti-cancer innovations. The ebook is split into 15 chapters, every one of in order to be concerned about one specific melanoma (breast, bladder, cervical, colorectal, esophageal, gastric, laryngeal, liver, lung, nasopharyngeal, pancreatic, prostate, thyroid, leukaemia and cutaneous malignant melanoma). a couple of validated leaders within the box have significantly summarized the hot discoveries referring to apoptosis in a selected melanoma and its capability for anti-cancer remedy. The publication describes how the apoptosis performs a job within the particular carcinogen-induced mobile and molecular adjustments throughout the improvement of the melanoma, and significantly discusses how the rising anti-cancer method could be equipped through the usage of the explicit carcinogen-related apoptotic pathway. consequently, this e-book might be not just for laboratory-based molecular and mobile biologists and biochemists in melanoma study but in addition for medical oncologists and people operating within the pharmaceutical and biotechnological industries.

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Extra info for Apoptosis in Carcinogenesis and Chemotherapy: Apoptosis in cancer

Sample text

Int J Oncol 20:155–159 Bonnet D, Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3:730–737 Bullani RR, Wehrli P, Viard-Leveugle I, Rimoldi D, Cerottini JC, Saurat JH, Tschopp J, French LE (2002) Frequent downregulation of Fas (CD95) expression and function in melanoma. Melanoma Res 12:263–270 Cheng EH, Kirsch DG, Clem RJ, Ravi R, Kastan MB, Bedi A, Ueno K, Hardwick JM (1997) Conversion of Bcl-2 to a Bax-like death effector by caspases.

Int J Cancer 97:458–465 Okada H, Mak TW (2004) Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer 4:592–603 Oltvai ZN, Korsmeyer SJ (1994) Checkpoints of dueling dimers foil death wishes. Cell 79:189–192 1 Apoptotic Signaling Pathway and Resistance to Apoptosis 21 Pardal R, Clarke MF, Morrison SJ (2003) Applying the principles of stem-cell biology to cancer. Nat Rev Cancer 3:895–902 Peng XH, Karna P, Cao Z, Jiang BH, Zhou M, Yang L (2006) Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression.

Cell Stem Cell 1:555–567 Guo Y, Mantel C, Hromas RA, Broxmeyer HE (2008) Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells 26:30–34 Hahm HA, Davidson NE (1998) Apoptosis in the mammary gland and breast cancer. EndocrineRelated Cancer 5:199–211 Han ZB, Ren H, Zhao H, Chi Y, Chen K, Zhou B, Liu YJ, Zhang L, Xu B, Liu B, Yang R, Han ZC (2008) Hypoxia-inducible factor (HIF)-1{alpha} directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF).

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Apoptosis in Carcinogenesis and Chemotherapy: Apoptosis in cancer by Prasanthi Karna, Lily Yang (auth.), George G. Chen Dr, Paul B.S. Lai Dr (eds.)


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