Terry Wikle Shapiro's A Clinical Guide to Stem Cell and Bone Marrow PDF

By Terry Wikle Shapiro

Stem mobile and Bone Marrow Transplantation

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Additional resources for A Clinical Guide to Stem Cell and Bone Marrow Transplantation

Sample text

J Clin Oncol. 1991;9:152–158. Page 29 Chapter 1— Pretransplant Evaluation Comprehensive pretransplant evaluation of the patient is essential both to determine the patient's ability to withstand the rigors of transplantation and to establish parameters that will provide a valuable basis for post-transplant evaluation. In the setting of allogeneic transplantation, thorough evaluation of a potential bone marrow/peripheral blood stem cell donor is performed to determine donor suitability. I. Patient Evaluation 1, 2 A.

London, England: Mosby-Wolfe; 1995:19–35. 11. Krivit W, Whitley CB, Chang P, et al. Lysosomal storage diseases treated by bone marrow transplantation. In: Gale RP, Champlin R, eds. Bone Marrow Transplantation: Current Controversies. New York: Alan R Liss; 1989:367–378. 12. Borgna-Pignatti C. Inherited defects in red cell production. In: Treleaven J, Wiernik P, eds. Bone Marrow Transplantation. London, England: Mosby-Wolfe; 1995:37–47. 13. Nagel RL. The dilemma of marrow transplantation in sickle cell anemia.

Most transplant centers will not attempt allogeneic transplantation with anything less than a five out of six HLA match. Even in related HLA-identical transplantation, 10% to 20% of recipients experience clinically significant GVHD. 3 This percentage is increased in unrelated HLA-identical transplants. H. With the advent of cell selection technology, studies are being conducted to consider the use of mismatched donors, such as haplotype matches, for allogeneic transplantation. Page 35 V. Donor Evaluation A.

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A Clinical Guide to Stem Cell and Bone Marrow Transplantation by Terry Wikle Shapiro


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